ODCs

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2 OMIM references -
1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
26 signs/symptoms

Lattice corneal dystrophy type I

Spondyloepiphyseal dysplasia congenita


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TGFBI	(0.62)	COL2A1

Citations in the biomedical literature:

Lattice corneal dystrophy type I		Spondyloepiphyseal dysplasia congenita
	Synonym(s): - Biber-Haab-Dimmer dystrophy - Classic lattice corneal dystrophy - LCD1 - LCDI - Lattice corneal dystrophy type 1		Synonym(s): - Congenital spondyloepiphyseal dysplasia - SEDC - Spranger-Wiedemann disease

	Classification (Orphanet): - Rare eye disease - Rare genetic disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease

	Classification (ICD10): - Diseases of the eye and adnexa -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: - Average age of death: - Type of inheritance: autosomal dominant

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references

Spondyloepiphyseal dysplasia congenita
	Very frequent - Abnormal vertebral size / shape - Autosomal dominant inheritance - Dysostosis / chondrodysplasia / osteodysplasia / osteochondrosis / skeletal dysplasia - Epiphyseal anomaly - Narrow rib cage / thorax - Short limbs / micromelia / brachymelia - Short neck - Short rib cage / thorax - Short stature / dwarfism / nanism Frequent - Broad forehead - Cleft palate without cleft lip / submucosal cleft palate / bifid uvula - Flat face - Hip dislocation / dysplasia / coxa valga / coxa vara / coxa plana - Hypertelorism - Lordosis - Osteoarthritis - Restricted joint mobility / joint stiffness / ankylosis - Talipes-varus / metatarsal varus Occasional - Cataract / lens opacification - Glaucoma - Hearing loss / hypoacusia / deafness - Kyphosis - Myopia - Nystagmus - Retinal detachment - Scoliosis
Lattice corneal dystrophy type I
(no data available)